About us

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Research Topics

The work of this research group is focused on the preparation, characterization and study of the catalytic and biological properties of metal complexes and nanostructured materials, specifically the lines of research are currently focused on:

- Preparation and study of the antitumor properties of new nanostructured materials functionalized with anticancer agents with potential application in chemotherapeutic treatments.

- Synthesis of intelligent controlled drug delivery systems based on biocompatible nanostructured materials with stoppers consisting of macromolecular systems with potential application for the prevention of the reproduction of bone tumors.

- Design of new chiral polyfunctional ligands with coordinating groups and chiral centers in their structure that are potentially reactive with the silanol groups present in the inorganic supports. Preparation of new hybrid titanium and copper materials that can act as catalysts in polymerization of polar monomers by ring opening, polymerization of olefins, oxidation of alcohols and asymmetric epoxidation of olefins in heterogeneous systems.

- Design and synthesis of metallic nanoparticles with high activity for oxidation processes, epoxidation and formation of C-C bonds.

- Design and development of photocatalysts based on doped titanium dioxide nanoparticles prepared using simple methods with large-scale industrial production and application possibilities, with potential application in hydrogen production, photo-oxidation, water decontamination and carbon dioxide recovery.

- Preparation of new hybrid materials with potential application in carbon dioxide valorization.


EQUIPMENT / USED TECHNIQUES

At present, the research group has access to two research laboratories, located in the departmental building I of the ESCET. The main equipment to which the research group can have access is the following:

  1. Lines that combine vacuum and inert atmosphere and that allow to work using Schlenk techniques.
  2. Solvent drying and deoxygenation systems.
  3. Controlled atmosphere box (dry box) for handling and storage of reagents.
  4. Agitation plates, stoves, baths and cryostats.
  5. Autoclave J.P. Selecta Preslave 75L.
  6. Carbolite 1100 muffle.
  7. Oven and high vacuum line.
  8. Buchi Reactor for polymerization tests up to pressures of 6 atmospheres.
  9. UV-Vis Analytik Jena Specord 200PC Spectrophotometer.
  10. Atomic Absorption Spectrometer Varian Spectr. AA50.
  11. FTIR Infrared Spectrophotometer 330 with Michelson filter interferometer.
  12. Varian Prostar high-resolution liquid chromatograph with DAD 335 detector.
  13. Autolab Potentiostat - Galvanostat PGSTAT302 Metrohm.
  14. Porosimeter Micromeritics ASAP 2020 for the determination of surface area, size and pore distribution.
  15. Gas Chromatograph with FID detector, Perkin-Elmer Clarus 580.

In addition, due to the possibility of accessing the facilities of the Technological Support Center (CAT of the URJC), the necessary techniques are available for the characterization of new organic, inorganic compounds and new nanostructured materials such as:

  • Varian-Mercury Plus NMR spectrometer (400 MHz).
  • Varian-Infinity Plus NMR spectrometer (400 MHz).
  • Phillips powder diffractometer model PW3040 / 00 X'Pert MPD / MRD.
  • Phillips MagiX X-ray fluorescence spectrophotometer with a 1kW X-ray source.
  • Philips ESEM Philips Scanning Electron Microscope with a Dispersive Energy Spectrometer (EDS) System.
  • Philips TECNAI 20 transmission electron microscope.

There are also access to some techniques of the Polymer Technology Laboratory (LATEP): for the adequate physico-chemical characterization of the polymers obtained, among which include:

  • Waters 150-C and Waters Alliance 2000 gel permeation chromatograph.

In addition, other instruments are currently available and in collaboration with various Departments of the ESCET, to which we have access, such as:

  • Setsys 18 A thermogravimetric analyzer (Setaram).

Finally, our research group due to its close collaboration with different Institutes or Research Groups has access, through the scientific collaborations that it maintains, to a different devices and techniques, some of them are described here:

  1. Several units of complete crops (booths, incubators, microscopes, autoclave, etc).
  2. Analytical flow cytometer FACSCalibur.
  3. Centrifuges, ultracentrifuges and table centrifuges.
  4. Plate reader, electroporator.
  5. Fluorescence and confocal microscope.
  6. 3100-Avant sequencing unit.
  7. Real-time quantitative PCR units.
  8. CD circular dicroism, Stopped-flow.
  9. Microcalorimetry unit.
  10. Image treatment unit.
  11. Protein and nucleic acid electrophoresis systems.

SERVICES OFFERED

Design, synthesis and characterization of a wide variety of metal complexes with applications in chemotherapeutic treatments (complexes of titanium, tin, gallium, palladium, ruthenium, etc.).

Design, synthesis and characterization of new porous nanostructured materials based on silica, alumina and hydroxyapatite. Preparation of hybrid materials. Study of functionalization reactions with agents with antitumor and catalytic properties. Study of the release of agents in the media studied.

The in vitro study of the cytotoxic properties of metal complexes and nanostructured materials against human cancer cells is also offered through collaborations with the different groups with which contact is maintained. Study of properties associated with the mechanism of cellular action of the agents studied.

Design, synthesis and characterization of a wide variety of organic and organometallic compounds with catalytic activity in catalytic and photocatalytic reactions.

Optimization and study of the catalytic properties of homogeneous and supported systems in polymerization and co-polymerization of olefins (ethylene, propylene, 1-hexene, 1-octene, 1-hexen-6-ol, 10-undecen-1-ol)

Preparation and characterization of mesoporous hybrid titanium and copper materials and preparation of metallic nanoparticles with specific characteristics

Electrochemical characterization of metallic complexes and metal complexes supported.

Optimization and study of the catalytic properties of homogeneous and supported catalytic systems in oxidation and asymmetric epoxidation.

Preparation of new materials based on nanostructures of porous titanium oxides doped with modulated properties. Study of the properties of materials in water decontamination by photocatalytic reactions.

Exhaustive study of materials based on titanium oxide to try an increase in photocatalytic activity, support in different materials for its application in hydrogen production and water decontamination and adaptation of these materials for their possible specific use in adsorption, capture, and oxidation / carbon dioxide reduction.


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